Neutropenia in patients with inflammatory arthritis treated with sulphasalazine.

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Neutropenia in patients with inflammatory arthritis treated with sulphasalazine.

This report describes two patients who developed severe neutropenia one month after starting sulphasalazine (SASP) as treatment for their inflammatory joint disease. Both recovered on stopping the drug. Six further cases (out of a series of 180 patients with inflammatory forms of arthritis receiving SASP therapy) in whom transient leucopenia occurred are also recorded. These patients were able ...

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Background:Methotrexate (MTX) is one of the most commonly used disease-modifying antirheumatic drugs in the treatment of rheumatoid arthritis (RA) which can be associated with toxic effects on different organs. This study was designed to investigate the hepatotoxic effects in RA patients treated with MTX. Methods: In this cross-sectional observational study, RA patients who received standard d...

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ژورنال

عنوان ژورنال: Annals of the Rheumatic Diseases

سال: 1986

ISSN: 0003-4967

DOI: 10.1136/ard.45.9.761